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Summary: MEK is phosphorylated and activated by RAF.
Summary: Reviewed: Restituito, S, 2008-11-27 12:38:49
Summary: Edited: Mahajan, SS, 2008-01-14 16:01:52
Summary: Reviewed: Peters, JM, 2006-03-27 22:55:09
Summary: Reviewed: Tukey, D, 2009-11-17
Summary: Edited: Mahajan, SS, 2011-05-23
Summary: Functional GABA B receptors are heteromers of GABA B1 and B2 subunits, complexed with G protein alpha-i, 0, beta, and gamma subunits. They function as metabotropic receptors. When GABA is bound to the B1 sub-unit, the B2 subunit undergoes a conformational change that releases the G alpha-i G0 dimer (which binds and inactivates cytosolic adenylate cyclase) and the G beta G gamma dimer (which activates the GIRK (KIR3) potassium channel) (Pinard et al. 2010).
Summary: Authored: Matthews, L, 2006-05-15 07:16:46