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Searched for: REACTOME AND Stabilization of mRNA by HuR [All Organisms, All Data Sources]

Your search has found 11 relevant records:

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Pathways (11)
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Pathway: Stabilization of mRNA by HuR  from Reactome  [19 molecules]
Edited: May, B, 2009-12-29.

Summary:  Edited: May, B, 2009-12-29

  • ... Stabilization of mRNA by HuR ...
  • ... Reactome ...
  • ... reactome.
  • ... export pathway to transfer the mRNA to the cytoplasm. ... The mechanism by which HuR shields the mRNA. ... products of HuR in turn promote apoptosis.
  • ... Reactome stable identifier. ...-induced stabilization and nuclear export of cyclooxygenase 2 mRNA ...
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Pathway: Stabilization of p53  from Reactome  [75 molecules]
Later studies pin-pointed that a single serine (Ser-15) was phosphorylated by ATM and phosphorylation of Ser-15 was rapidly-induced in IR-treated cells and this response was ATM-dependent (Canman et al, 1998; Banin et al, 1998 and Khanna et al, 1998).

Summary:  Later studies pin-pointed that a single serine (Ser-15) was phosphorylated by ATM and phosphorylation of Ser-15 was rapidly-induced in IR-treated cells and this response was ATM-dependent (Canman et al, 1998; Banin et al, 1998 and Khanna et al, 1998). ATM also regulates the phosphorylation of p53 at other sites, especially Ser-20, by activating other serine/threonine kinases in response to IR (Chehab et al, 2000; Shieh et al, 2000; Hirao et al 2000). Phosphorylation of p53 at Ser-20 interferes with p53-MDM2 interaction. MDM2 is transcriptionally activated by p53 and is a negative regulator of p53 that targets it for degradation (Haupt et al, 1997; Kubbutat et al, 1997). In addition modification of MDM2 by ATM also affects p53 stabilization (Maya et al, 2001).

  • ... Stabilization of p53 ...
  • ... Reactome ...
  • ... reactome.
  • ... stabilization (Maya et al, 2001).
  • ... Reactome stable identifier. ... Use this URL to connect to the web page of this instance in Reactome: http://www. ...reactome.
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Pathway: Association of TriC/CCT with target proteins during biosynthesis  from Reactome  [14 molecules]
Authored: Matthews, L, 2008-12-01 04:46:41.

Summary:  Authored: Matthews, L, 2008-12-01 04:46:41

  • ... to stabilization of newly made proteins with complex topologies ...
  • ... Reactome stable identifier. ... Use this URL to connect to the web page of this instance in Reactome: http://www. ...reactome. ...Association of TriC/CCT with target proteins during biosynthesis ...
  • ... Reactome ...
  • ... to the web page of this instance in Reactome: http://www. ...reactome.
  • ... REACTOME DATABASE ID ...
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Pathway: Gap junction assembly  from Reactome  [19 molecules]
Authored: Gilleron, J, Segretain, D, Falk, MM, 2007-01-03 12:23:09.

Summary:  Authored: Gilleron, J, Segretain, D, Falk, MM, 2007-01-03 12:23:09

  • ... Reactome ...
  • ... reactome.
  • ... , and (9) stabilization of peripheral microtubule plus-ends by binding to Cx43-based gap junctions (see. ... Use this URL to connect to the web page of this instance in Reactome: http://www. ...reactome.
  • ... REACTOME DATABASE ID ...
  • ... Reactome stable identifier. ... Use this URL to connect to the web page of this instance ...
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Pathway: Regulation of activated PAK-2p34 by proteasome mediated degradation  from Reactome  [72 molecules]
Stimulation of cell death by PAK-2 requires the generation and stabilization of the caspase-activated form, PAK-2p34 (Walter et al.

Summary:  Stimulation of cell death by PAK-2 requires the generation and stabilization of the caspase-activated form, PAK-2p34 (Walter et al., 1998;Jakobi et al., 2003). Levels of proteolytically activated PAK-2p34 protein are controlled by ubiquitin-mediated proteolysis. PAK-2p34 but not full-length PAK-2 is degraded by the 26 S proteasome (Jakobi et al., 2003). It is not known whether ubiquitination and degradation of PAK-2p34 occurs in the cytoplasm or in the nucleus.

  • ... Reactome ...
  • ... the generation and stabilization of the caspase-activated form, PAK-2p34 (Walter et al.
  • ... Reactome stable identifier. ... Use this URL to connect to the web page of this instance in Reactome: http://www. ...reactome.
  • ... REACTOME ...
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Pathway: vRNA Synthesis  from Reactome  [14 molecules]
Authored: Bortz, E, Garcia-Sastre, A, 2007-02-12 19:39:05.

Summary:  Authored: Bortz, E, Garcia-Sastre, A, 2007-02-12 19:39:05

  • ... Reactome ...
  • ... reactome.
  • ... this URL to connect to the web page of this instance in Reactome: http://www. ...reactome.
  • ... REACTOME DATABASE ID ...
  • Model suggesting that replication of influenza virus is regulated by stabilization of replicative intermediates ...
  • ... Reactome stable identifier.
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Pathway: ADP signalling through P2Y purinoceptor 1  from Reactome  [19 molecules]
Authored: Jupe, S, 2009-04-24 10:43:00.

Summary:  Authored: Jupe, S, 2009-04-24 10:43:00

  • ... stabilization.
  • ... Reactome stable identifier. ... Use this URL to connect to the web page of this instance in Reactome: http://www. ...reactome.
  • ... REACTOME ...
  • ... Use this URL to connect to the web page of this instance in Reactome: http://www. ...reactome.
  • ... Reactome ...
  • ... reactome.
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Pathway: ADP signalling through P2Y purinoceptor 12  from Reactome  [15 molecules]
Authored: Jassal, B, 2009-02-27 14:41:36.

Summary:  Authored: Jassal, B, 2009-02-27 14:41:36

  • ... stabilization.
  • ... Reactome stable identifier. ... Use this URL to connect to the web page of this instance in Reactome: http://www. ...reactome.
  • ... REACTOME ...
  • ... Use this URL to connect to the web page of this instance in Reactome: http://www. ...reactome.
  • ... Reactome ...
  • ... reactome.
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Pathway: Gap junction trafficking  from Reactome  [43 molecules]
Authored: Gilleron, J, Segretain, D, Falk, MM, 2007-01-03 12:23:09.

Summary:  Authored: Gilleron, J, Segretain, D, Falk, MM, 2007-01-03 12:23:09

  • ... Reactome ...
  • ... reactome.
  • ... ) aggregation of individual gap junction channels into plaques, (9) stabilization of peripheral. ..., and phosphorylation of connexin43 in brefeldin A-treated rat mammary tumor cells ...
  • ... Reactome stable identifier. ... Use this URL to connect to the web page of this instance in Reactome: http://www. ...reactome.
  • ... REACTOME 271828 ...
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Pathway: cRNA Synthesis  from Reactome  [15 molecules]
Authored: Bortz, E, Garcia-Sastre, A, 2007-02-12 19:39:05.

Summary:  Authored: Bortz, E, Garcia-Sastre, A, 2007-02-12 19:39:05

  • ... Reactome ...
  • ... reactome.
  • ... Reactome stable identifier. ... Use this URL to connect to the web page of this instance in Reactome: http://www. ...reactome.
  • ... REACTOME ...
  • ... Use this URL to connect to the web page of this instance in Reactome: http://www. ...reactome.