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Searched for: REACTOME AND Removal of the Flap Intermediate [All Organisms, All Data Sources]

Your search has found 32 relevant records:

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Pathways (32)Molecules (6)
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Pathway: Removal of the Flap Intermediate from the C-strand  from Reactome  [27 molecules]
Two endonucleases, Dna2 and flap endonuclease 1 (FEN-1), are responsible for resolving the nascent flap structure (Tsurimoto and Stillman 1991).

Summary:  Two endonucleases, Dna2 and flap endonuclease 1 (FEN-1), are responsible for resolving the nascent flap structure (Tsurimoto and Stillman 1991). The Dna2 endonuclease/helicase in yeast is a monomer of approximately 172 kDa. Human FEN-1 is a single polypeptide of approximately 42 kDa. Replication Protein A regulates the switching of endonucleases during the removal of the displaced flap.

  • ... Removal of the Flap Intermediate from the C-strand ...
  • ... Reactome ...
  • ... reactome.
  • Two endonucleases, Dna2 and flap endonuclease 1 (FEN-1), are responsible for resolving the nascent flap structure (Tsurimoto and Stillman 1991). ... The Dna2 endonuclease/helicase. ... Replication Protein A regulates the switching of endonucleases during the removal of the displaced ...
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Pathway: Removal of the Flap Intermediate  from Reactome  [44 molecules]
Two endonucleases, Dna2 and flap endonuclease 1 (FEN-1), are responsible for resolving the nascent flap structure (Tsurimoto and Stillman 1991).

Summary:  Two endonucleases, Dna2 and flap endonuclease 1 (FEN-1), are responsible for resolving the nascent flap structure (Tsurimoto and Stillman 1991). The Dna2 endonuclease/helicase in yeast is a monomer of approximately 172 kDa. Human FEN-1 is a single polypeptide of approximately 42 kDa. Replication Protein A regulates the switching of endonucleases during the removal of the displaced flap.

  • ... Removal of the Flap Intermediate ...
  • ... Reactome ...
  • ... reactome.
  • Two endonucleases, Dna2 and flap endonuclease 1 (FEN-1), are responsible for resolving the nascent flap structure. ... the switching of endonucleases during the removal of the displaced flap.
  • ... Use this URL to connect to the web page of this instance in Reactome: http://www. ...reactome.
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Pathway: Removal of DNA patch containing abasic residue  from Reactome  [44 molecules]
During removal of DNA patch containing abasic residue, DNA glycosylase is displaced by APE1 which endonucleolytically cleaves the 5' side of the base-free deoxyribose residue.

Summary:  During removal of DNA patch containing abasic residue, DNA glycosylase is displaced by APE1 which endonucleolytically cleaves the 5' side of the base-free deoxyribose residue. POL Beta is recruited to the AP site where it mediates incorporation of the first replacement nucleotide. Association of POL delta with the AP site displaces POL Beta. DNA strand displacement synthesis then follows and flap structures are cleaved.

  • ... Removal of DNA patch containing abasic residue ...
  • ... Reactome ...
  • ... reactome.
  • During removal of DNA patch containing abasic residue, DNA glycosylase is displaced by APE1. ... and flap structures are cleaved.
  • ... Use this URL to connect to the web page of this instance in Reactome: http://www. ...reactome.
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Pathway: Removal of licensing factors from origins  from Reactome  [109 molecules]
Licensing factors are removed from the origin by various means like biochemical modification (phosphorylation) or by physical association with other proteins.

Summary:  Licensing factors are removed from the origin by various means like biochemical modification (phosphorylation) or by physical association with other proteins. This pathway includes the annotations of events in which the fates of different proteins at the origin are outlined.

  • ... Removal of licensing factors from origins ...
  • ... Reactome ...
  • ... reactome.
  • ... Removal of licensing factors from origins 271828. ... Use this URL to connect to the web page of this instance in Reactome: http://www. ...reactome.
  • ... REACTOME DATABASE ID ...
  • ... Reactome stable identifier. ... Use this URL to connect to the web page of this instance in Reactome: http ...
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Pathway: Cholesterol biosynthesis  from Reactome  [70 molecules]
Authored: Jassal, B, 2007-01-24 15:15:12.

Summary:  Authored: Jassal, B, 2007-01-24 15:15:12

  • ... Reactome ...
  • ... reactome.
  • ... , including the removal of three methyl groups, the reduction of one double bond and the migration. ... page of this instance in Reactome: http://www. ...reactome.
  • ... REACTOME DATABASE ID ...
  • ... Reactome stable identifier. ... Use this URL to connect to the web page of this instance ...
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Pathway: Base-free sugar-phosphate removal via the single-nucleotide replacement pathway  from Reactome  [26 molecules]
Base-free sugar-phosphate removal via the single-nucleotide replacement pathway requires displacement of DNA glycosylase by APE1, APE1 mediated endonucleolytic cleavage at the 5' side of the base-free deoxyribose residue, recruitment of POL Beta to the AP site and Excision of the abasic sugar phosphate (dRP) residue at the strand break (Lindahl and Wood, 1999).

Summary:  Base-free sugar-phosphate removal via the single-nucleotide replacement pathway requires displacement of DNA glycosylase by APE1, APE1 mediated endonucleolytic cleavage at the 5' side of the base-free deoxyribose residue, recruitment of POL Beta to the AP site and Excision of the abasic sugar phosphate (dRP) residue at the strand break (Lindahl and Wood, 1999).

  • Base-free sugar-phosphate removal via the single-nucleotide replacement pathway ...
  • ... Reactome. ... sugar-phosphate removal via the single-nucleotide replacement pathway ...
  • Base-free sugar-phosphate removal via the single-nucleotide replacement pathway requires displacement of DNA glycosylase. ... Use this URL to connect to the web page of this instance in Reactome: http://www. ...reactome.
  • ... REACTOME DATABASE ID ...
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Pathway: CDK-mediated phosphorylation and removal of Cdc6  from Reactome  [73 molecules]
As cells enter S phase, HsCdc6p is phosphorylated by CDK promoting its export from the nucleus (see Bell and Dutta 2002).

Summary:  As cells enter S phase, HsCdc6p is phosphorylated by CDK promoting its export from the nucleus (see Bell and Dutta 2002).

  • CDK-mediated phosphorylation and removal of Cdc6 ...
  • ... Reactome ...
  • ... reactome.
  • CDK-mediated phosphorylation and removal.
  • ... Reactome stable identifier. ... Use this URL to connect to the web page of this instance in Reactome. ... REACTOME ...
  • ... Use this URL to connect to the web page of this instance in Reactome ...
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Pathway: mRNA Splicing  from Reactome  [183 molecules]
The process in which excision of introns from the primary transcript of messenger RNA (mRNA) is followed by ligation of the two exon termini exposed by removal of each intron, is called mRNA splicing.

Summary:  The process in which excision of introns from the primary transcript of messenger RNA (mRNA) is followed by ligation of the two exon termini exposed by removal of each intron, is called mRNA splicing. Most of the mRNA is spliced by the major pathway, involving the U1, U2, U4, U5 and U6 snRNPs. A minor fraction, about 1 %, of the mRNAs are spliced via the U12 dependent pathway.

  • ... Reactome ...
  • ... reactome.
  • ... by removal of each intron, is called mRNA splicing. ... Most of the mRNA is spliced by the major pathway. ... of this instance in Reactome: http://www. ...reactome.
  • ... REACTOME DATABASE ID ...
  • ... Reactome stable identifier. ... Use this URL to connect to the web page of this instance in Reactome: http://www. ...reactome.
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Pathway: Orc1 removal from chromatin  from Reactome  [98 molecules]
  • Orc1 removal from chromatin ...
  • ... Reactome ...
  • ... reactome.
  • ... Reactome stable identifier. ... Use this URL to connect to the web page of this instance in Reactome: http://www. ...reactome.
  • ... REACTOME ...
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Pathway: Removal of aminoterminal propeptides from gamma-carboxylated proteins  from Reactome  [15 molecules]
Authored: D'Eustachio, P, 2005-03-17 16:24:57.

Summary:  Authored: D'Eustachio, P, 2005-03-17 16:24:57

  • ... Removal of aminoterminal propeptides from gamma-carboxylated proteins ...
  • ... Reactome ...
  • ... reactome.
  • ... Removal. ... to the cell membrane or secreted from the cell via pathways to be annotated in a future release of Reactome.
  • ... Use this URL to connect to the web page of this instance in Reactome: http://www. ...reactome.
  • ... REACTOME DATABASE ...