This portal has not been updated since October 2011. Please use the new PC2 web services.
Send us your feedback.  Sign up for Pathway Commons announcements.  RSS Logo RSS Feed

Searched for: REACTOME AND Recruitment of mitotic centrosome proteins and complexes [All Organisms, All Data Sources]

Your search has found 58 relevant records:

Narrow Results:

Pathways (58)Molecules (1)
Showing Results 1 - 10 of 58  | Next 10
0%0%
Pathway: Recruitment of mitotic centrosome proteins and complexes  from Reactome  [86 molecules]
Edited: Matthews, L, 2008-11-09 05:12:41.

Summary:  Edited: Matthews, L, 2008-11-09 05:12:41

  • ... Recruitment of mitotic centrosome proteins and complexes ...
  • ... Reactome ...
  • ... reactome.
  • The mitotic spindle. ... additional gamma TuRC complexes and acquiring mitosis-associated centrosomal proteins including NuMA, Plk1 ...
0%0%
Pathway: Recruitment of NuMA to mitotic centrosomes  from Reactome  [22 molecules]
Edited: Matthews, L, 2008-11-09 05:12:41.

Summary:  Edited: Matthews, L, 2008-11-09 05:12:41

  • ... Recruitment of NuMA to mitotic centrosomes ...
  • ... Reactome ...
  • ... reactome.
  • ... Recruitment of NuMA to mitotic centrosomes 271828. ... Although NuMA is not a bona fide constituent of the mitotic centrosome. ... The mitotic activation of NuMA. ... is transported to the mitotic poles where it forms an insoluble crescent around centrosomes ...
0%0%
Pathway: p75NTR recruits signalling complexes  from Reactome  [28 molecules]
Authored: Nasi, S, Annibali, D, 2006-10-10 09:07:07.

Summary:  Authored: Nasi, S, Annibali, D, 2006-10-10 09:07:07

  • ... p75NTR recruits signalling complexes ...
  • ... Reactome ...
  • ... reactome.
  • NF-kB activation involves recruitment at the cell membrane of several proteins such as RIP2, MYD88, IRAK1, TRAF6, p62 and atypical PKC by the NGF:p75NTR complex.
  • ... Reactome stable identifier ...
0%0%
Pathway: Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins  from Reactome  [87 molecules]
Reviewed: Peters, JM, 2006-03-27 22:55:09.

Summary:  Reviewed: Peters, JM, 2006-03-27 22:55:09

  • Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins ...
  • ... Reactome 271828. ... of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins ...
  • ... /C by mitotic kinases as well as recruitment of the APC/C activator protein Cdc20. ... Use this URL to connect to the web page of this instance in Reactome: http://www. ...reactome.
  • ... REACTOME DATABASE ID 271828 ...
0%0%
Pathway: Activation of ATR in response to replication stress  from Reactome  [61 molecules]
Authored: Borowiec, JA, 2006-02-25 17:40:15.

Summary:  Authored: Borowiec, JA, 2006-02-25 17:40:15

  • ... of Cdk1-cyclin B complexes. ... In response to replication stress, Chk1 phosphorylates Cdc25B and Cdc25C leading to Cdc25B/C complex formation with 14-3-3 proteins. ... As these complexes are sequestered. ...Activation of ATR in response to replication stress ...
  • ... Reactome ...
  • ... reactome. ... or the repair of DNA damage. ... The persistent ssDNA also stimulates recruitment of the RFC-like Rad17ââ‚Â. ... Cdc25A also has mitotic functions. ... Phosphorylation of Cdc25A at Ser125 by Chk1 ...
0%0%
Pathway: Nuclear Receptor transcription pathway  from Reactome  [3 molecules]
Reviewed: Freedman, LP, 2009-08-29.

Summary:  Reviewed: Freedman, LP, 2009-08-29

  • ... ) was found to result in the recruitment of a specific complex of Thyroid Receptor Associated Proteins. ... in the recruitment of a specific complex of D Receptor Interacting Proteins - the DRIP coactivator.
  • ... Reactome ...
  • ... reactome.
  • ... is the family of Nuclear Receptor (NR) proteins. ... specific corepressor complexes of the NCOR/SMRT type, to mediate transcriptional repression ...
0%0%
Pathway: Recruitment of repair and signaling proteins to double-strand breaks  from Reactome  [19 molecules]
Authored: Matthews, L, 2003-11-18 00:00:00.

Summary:  Authored: Matthews, L, 2003-11-18 00:00:00

  • ... Recruitment of repair and signaling proteins to double-strand breaks ...
  • ... Reactome ...
  • ... reactome.
  • Following exposure to ionizing radiation, a number of recombination/repair proteins and complexes. ... These proteins include gamma-H2AX, ATM, RAD51, BRCA1, BRCA2, NBS1, RPA, and MDC1/NFBD1 ...
0%0%
Pathway: APC/C-mediated degradation of cell cycle proteins  from Reactome  [124 molecules]
The Anaphase Promoting Complex or Cyclosome (APC/C) functions during mitosis to promote sister chromatid separation and mitotic exit through the degradation of mitotic cyclins and securin.

Summary:  The Anaphase Promoting Complex or Cyclosome (APC/C) functions during mitosis to promote sister chromatid separation and mitotic exit through the degradation of mitotic cyclins and securin. This complex is also active in interphase insuring the appropriate length of the G1 phase (reviewed in Peters, 2002). The APC/C contains at least 12 subunits and functions as an ubiquitin-protein ligase (E3) promoting the multiubiquitination of its target proteins (see Gieffers et al., 2001).

  • APC/C-mediated degradation of cell cycle proteins ...
  • ... Reactome ...
  • ... reactome. ... degration of mitotic cyclins and other mitotic proteins culminating with its own ubiquitin-conjugating. ... proteins ...
  • The Anaphase Promoting Complex or Cyclosome (APC/C) functions during mitosis to promote sister chromatid separation and mitotic exit through the degradation of mitotic cyclins. ... ligase (E3) promoting the multiubiquitination of its target proteins (see Gieffers et al.
0%0%
Pathway: RNA Polymerase III Transcription Initiation From Type 1 Promoter  from Reactome  [31 molecules]
The type 1 promoters recruit TFIIIA, the founding member of the C2H2 zinc finger family of DNA-binding proteins (Engelke et al.

Summary:  The type 1 promoters recruit TFIIIA, the founding member of the C2H2 zinc finger family of DNA-binding proteins (Engelke et al., 1980; Sakonju et al., 1981). The binding of TFIIIA then allows the binding of TFIIC (Lassar et al., 1983), a complex consisting of five subunits (which differs from the six subunits in S. cerevisiae) in human cells and S. pombe. Once the DNA/TFIIIA/TFIIIC complex is formed, Brf1-TFIIIB joins the complex and this in turn allows the recruitment of RNA polymerase III (Bieker et al., 1985; Setzer and Brown, 1985).

  • ... Transcription of class III genes: formation of preinitiation complexes ...
  • ... Reactome.
  • ... Reactome ...
  • ... member of the C2H2 zinc finger family of DNA-binding proteins (Engelke et al. ... allows the recruitment of RNA polymerase III (Bieker et al. ... Use this URL to connect to the web page of this instance in Reactome: http ...
0%0%
Pathway: NOD1/2 Signaling Pathway  from Reactome  [52 molecules]
Reviewed: Rittinger, K, 2011-06-06.

Summary:  Reviewed: Rittinger, K, 2011-06-06

  • ... Reactome ...
  • ... reactome.
  • ... release from IkappaB proteins. ... NOD1 and NOD2 signaling involves an interaction between their caspase-recruitment domain (CARD) and the CARD of the kinase RIPK2 (RIP2/RICK). ... their NACHT domains, inducing physical proximity of RIP2 proteins that is believed to trigger their K63-linked polyubiquitination, facilitating recruitment of the TAK1 complex.