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Searched for: REACTOME AND RNA Polymerase II Transcription [All Organisms, All Data Sources]

Your search has found 136 relevant records:

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Pathways (136)Molecules (102)
Showing Results 1 - 10 of 136  | Next 10
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Pathway: RNA Polymerase II Pre-transcription Events  from Reactome  [101 molecules]
  • ... RNA Polymerase II Pre-transcription Events ...
  • ... Reactome ...
  • ... reactome.
  • ... Reactome stable identifier. ... Use this URL to connect to the web page of this instance in Reactome: http://www. ...reactome.
  • ... REACTOME ...
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Pathway: RNA Polymerase II Transcription Initiation And Promoter Clearance  from Reactome  [76 molecules]
  • ... RNA Polymerase II Transcription Initiation And Promoter Clearance ...
  • ... Reactome ...
  • ... reactome.
  • ... Use this URL to connect to the web page of this instance in Reactome: http://www. ...reactome.
  • ... REACTOME DATABASE ID ...
  • ... Reactome stable identifier.
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Pathway: RNA Polymerase II Transcription  from Reactome  [220 molecules]
  • ... RNA Polymerase II Transcription ...
  • ... Reactome ...
  • ... reactome.
  • ... Use this URL to connect to the web page of this instance in Reactome: http://www. ...reactome.
  • ... REACTOME DATABASE ID ...
  • ... Reactome stable identifier. ... Use this URL to connect to the web page of this instance in Reactome: http ...
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Pathway: RNA Polymerase II Transcription Termination  from Reactome  [84 molecules]
Edited: Joshi-Tope, G, 0000-00-00 00:00:00.

Summary:  Edited: Joshi-Tope, G, 0000-00-00 00:00:00

  • ... RNA Polymerase II Transcription Termination ...
  • ... Reactome ...
  • ... reactome.
  • ... RNA Polymerase II Transcription Termination.
  • ... Reactome stable identifier. ... Use this URL to connect to the web page of this instance in Reactome: http://www. ...reactome.
  • ... REACTOME ...
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Pathway: RNA Polymerase II Promoter Escape  from Reactome  [61 molecules]
Authored: Timmers, H.

Summary:  Authored: Timmers, H. T. M., 2003-09-11 07:42:30

  • ... RNA Polymerase II Promoter Escape ...
  • ... Reactome ...
  • ... reactome.
  • ... RNA Polymerase II promoter escape occurs after the first.
  • Three transitions in the RNA polymerase II transcription complex during initiation.
  • ... Reactome stable identifier.
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Pathway: RNA Polymerase II Transcription Pre-Initiation And Promoter Opening  from Reactome  [53 molecules]
Formation of the pre-initiation complex.

Summary:  Formation of the pre-initiation complex

  • ... RNA Polymerase II Transcription Pre-Initiation And Promoter Opening ...
  • ... Reactome ...
  • ... reactome.
  • The general transcription factors of RNA polymerase II.
  • ... Use this URL to connect to the web page of this instance in Reactome: http ...
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Pathway: RNA Polymerase II Transcription Initiation  from Reactome  [58 molecules]
Authored: Timmers, H.

Summary:  Authored: Timmers, H. T. M., 2003-09-11 07:42:30

  • ... RNA Polymerase II Transcription Initiation ...
  • ... Reactome ...
  • ... reactome.
  • ... RNA Polymerase II Transcription Initiation 271828. ... of the general transcription factors during RNA polymerase II transcription.
  • ... of a four-nucleotide RNA commits RNA polymerase II to promoter escape.
  • ... Reactome. ... the template strand to the catalytic center of the RNA polymerase II enzyme.
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Pathway: RNA Polymerase III Transcription  from Reactome  [70 molecules]
Authored: Hernandez, N, 2003-09-11 07:42:29.

Summary:  Authored: Hernandez, N, 2003-09-11 07:42:29

  • ... RNA Polymerase III Transcription ...
  • ... Reactome ...
  • ... reactome.
  • Authored: Hernandez. ... of RNA polymerase II elongation, whereas some others have still unknown functions. ... Like other RNA. ..., and associated proteins mediate selective transcription by RNA polymerase III of genes with upstream.
  • ... RNA polymerase III Transcription Complexes ...
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Pathway: RNA Polymerase II Transcription Elongation  from Reactome  [73 molecules]
The mechanisms governing the process of elongation during eukaryotic mRNA synthesis are being unraveled by recent studies.

Summary:  The mechanisms governing the process of elongation during eukaryotic mRNA synthesis are being unraveled by recent studies. These studies have led to the expected discovery of a diverse collection of transcription factors that directly regulate the activities of RNA Polymerase II and unexpected discovery of roles for many elongation factors in other basic processes like DNA repair, recombination, etc. The transcription machinery and structural features of the major RNA polymerases are conserved across species. The genes active during elongation fall under different classes like, housekeeping, cell-cycle regulated, development and differentiation specific genes etc. The list of genes involved in elongation has been growing in recent times, and include: -TFIIS,DSIF, NELF, P-Tefb etc. that are involved in drug induced or sequence-dependent arrest - TFIIF, ELL, elongin, elongator etc. that are involved in increasing the catalytic rate of elongation by altering the Km and/or the Vmax of Pol II -FACT, Paf1 and other factors that are involved chromatin modification - DNA repair proteins, RNA processing and export factors, the 19S proteasome and a host of other factors like Spt5-Spt5, Paf1, and NELF complexes, FCP1P etc. (Arndt and Kane, 2003). Elongation also represents processive phase of transcription in which the activities of several mRNA processing factors are coupled to transcription through their binding to RNA polymerase (Pol II). One of the key events that enables this interaction is the differential phosphorylation of Pol II CTD. Phosphorylation pattern of CTD changes during transcription, most significantly at the beginning and during elongation process. TFIIH-dependent Ser5 phosphorylation is observed primarily at promoter regions while P-Tefb mediated Ser2 phosphorylation is seen mainly in the coding regions, during elongation. Experimental evidence suggests a dynamic association of RNA processing factors with differently modified forms of the polymerase during the transcription cycle. (Komarnitsky et al., 2000). [Komarnitsky et al 2000, Arndt & Kane 2003, Shilatifard et al 2003]

  • ... RNA Polymerase II Transcription Elongation ...
  • ... Reactome ...
  • ... reactome.
  • ... RNA Polymerase II Transcription Elongation 271828. ... of transcription factors that directly regulate the activities of RNA Polymerase II and unexpected. ... to transcription through their binding to RNA polymerase (Pol II).
  • Different phosphorylated forms of RNA polymerase II ...
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Pathway: Formation of the Early Elongation Complex  from Reactome  [48 molecules]
Authored: Gopinathrao, G, 2004-05-06 22:00:00.

Summary:  Authored: Gopinathrao, G, 2004-05-06 22:00:00

  • ... Transcription elongation by RNA polymerase II. ... transcription elongation through binding to a DRB sensitivity-inducing factor/RNA polymerase II.
  • Control of elongation by RNA polymerase II.
  • ... in transcription by Pol II is greatly impaired by protein kinase inhibitors such as 5,6-dichloro-1.
  • ... Reactome ...
  • ... reactome.