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Searched for: REACTOME AND Pyrimidine biosynthesis [All Organisms, All Data Sources]

Your search has found 12 relevant records:

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Pathways (12)Molecules (2)
Showing Results 1 - 10 of 12  | Next 10
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Pathway: Pyrimidine metabolism  from Reactome  [113 molecules]
Edited: D'Eustachio, P, 0000-00-00 00:00:00.

Summary:  Edited: D'Eustachio, P, 0000-00-00 00:00:00

  • ... Pyrimidine metabolism ...
  • ... Reactome ...
  • ... reactome.
  • ... to uridine 5'-monophosphate (UMP), the biosynthesis of other pyrimidine ribo- and deoxyribonucleotides. ...) and is then decarboxylated to form the pyrimidine nucleotide UMP. ...PBPyrimidine biosynthesis.
  • The events of human pyrimidine metabolism are conveniently, if somewhat ...
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Pathway: Pyrimidine salvage reactions  from Reactome  [37 molecules]
In pyrimidine salvage reactions, nucleosides and free bases generated by DNA and RNA breakdown are converted back to nucleotide monophosphates, allowing them to re-enter the pathways of pyrimidine biosynthesis (interconversion).

Summary:  In pyrimidine salvage reactions, nucleosides and free bases generated by DNA and RNA breakdown are converted back to nucleotide monophosphates, allowing them to re-enter the pathways of pyrimidine biosynthesis (interconversion).

  • ... Pyrimidine salvage reactions ...
  • ... Reactome ...
  • ... reactome.
  • In pyrimidine salvage. ... monophosphates, allowing them to re-enter the pathways of pyrimidine biosynthesis (interconversion.
  • Hereditary orotic aciduria and other disorders of pyrimidine metabolism ...
  • ... Reactome stable identifier.
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Pathway: Pyrimidine biosynthesis  from Reactome  [41 molecules]
Reviewed: Graves, L, Rush, MG, 0000-00-00 00:00:00.

Summary:  Reviewed: Graves, L, Rush, MG, 0000-00-00 00:00:00

  • ... Pyrimidine biosynthesis ...
  • ... Reactome ...
  • ... reactome.
  • ... Pyrimidine nucleotide biosynthesis in animals: genes, enzymes, and regulation.
  • The pyrimidine orotate (orotic acid) is synthesized in a sequence of four reactions, deriving. ... in the direction of UMP biosynthesis in the normal cell.
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Pathway: Pyrimidine catabolism  from Reactome  [59 molecules]
In parallel sequences of three reactions each, thymine is converted to beta-aminoisobutyrate and uracil is converted to beta-alanine.

Summary:  In parallel sequences of three reactions each, thymine is converted to beta-aminoisobutyrate and uracil is converted to beta-alanine. Both of these molecules are excreted in human urine and appear to be normal end products of pyrimidine catabolism (Griffith 1986; Webster et al. 2001). Mitochondrial AGXT2, however, can also catalyze the transamination of both molecules with pyruvate, yielding 2-oxoacids that can be metabolized further by reactions of branched-chain amino acid and short-chain fatty acid catabolism (Tamaki et al. 2000). The importance of these reactions in normal human pyrimidine catabolism has not been well worked out.

  • ... Pyrimidine catabolism ...
  • ... Reactome ...
  • ... reactome.
  • ... of these molecules are excreted in human urine and appear to be normal end products of pyrimidine. ... The importance of these reactions in normal human pyrimidine catabolism has not been well worked out.
  • ... Reactome stable identifier.
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Pathway: Recognition and association of DNA glycosylase with site containing an affected pyrimidine  from Reactome  [31 molecules]
Base excision repair is initiated by a DNA glycosylase which first recognizes and removes a damaged or incorrect (e.

Summary:  Base excision repair is initiated by a DNA glycosylase which first recognizes and removes a damaged or incorrect (e.g. mismatched) base.

  • Recognition and association of DNA glycosylase with site containing an affected pyrimidine ...
  • ... Reactome ...
  • ... reactome.
  • Recognition and association of DNA glycosylase with site containing an affected pyrimidine 271828.
  • ... Reactome stable identifier. ... Use this URL to connect to the web page of this instance in Reactome: http://www. ...reactome.
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Pathway: Cleavage of the damaged pyrimidine  from Reactome  [42 molecules]
Damaged pyrimidines are first cleaved by pyrimide-specific glycosylases (see Lindahl and Wood 1999).

Summary:  Damaged pyrimidines are first cleaved by pyrimide-specific glycosylases (see Lindahl and Wood 1999).

  • Cleavage of the damaged pyrimidine ...
  • ... Reactome ...
  • ... reactome.
  • ... Reactome stable identifier. ... Use this URL to connect to the web page of this instance in Reactome: http://www. ...reactome.
  • ... REACTOME ...
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Pathway: 5-Phosphoribose 1-diphosphate biosynthesis  from Reactome  [11 molecules]
Edited: D'Eustachio, P, 0000-00-00 00:00:00.

Summary:  Edited: D'Eustachio, P, 0000-00-00 00:00:00

  • ... 5-Phosphoribose 1-diphosphate biosynthesis ...
  • PRPP biosynthesis ...
  • ... Reactome ...
  • ... 1-diphosphate biosynthesis ...
  • ... in both the de novo and salvage pathways of purine and pyrimidine synthesis. ... Use this URL to connect to the web page of this instance in Reactome: http://www. ...reactome.
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Pathway: Depyrimidination  from Reactome  [42 molecules]
Authored: Matthews, L, 2004-02-09 03:00:00.

Summary:  Authored: Matthews, L, 2004-02-09 03:00:00

  • ... Reactome ...
  • ... reactome.
  • ... Depyrimidination of a damaged nucleotide is mediated by a pyrimidine-specific DNA glycosylase. ... to connect to the web page of this instance in Reactome: http://www. ...reactome.
  • ... REACTOME DATABASE ID ...
  • ... Reactome stable ...
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Pathway: Metabolism of nucleotides  from Reactome  [254 molecules]
Edited: D'Eustachio, P, Gillespie, ME, Joshi-Tope, G, 0000-00-00 00:00:00.

Summary:  Edited: D'Eustachio, P, Gillespie, ME, Joshi-Tope, G, 0000-00-00 00:00:00

  • ... Reactome ...
  • ... pThe movement of nucleotides and purine and pyrimidine bases across lipid bilayer membranes. ... in Reactome: http://www. ...reactome.
  • ... REACTOME. ... and pyrimidine metabolism in human apicomplexan parasites ...
  • ... Reactome stable identifier.
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Pathway: Translesion synthesis by Pol zeta  from Reactome  [7 molecules]
Pol zeta consists of two proteins: HREV3 with polymerase activity and HREV7, an accessory factor with unidentified activity.

Summary:  Pol zeta consists of two proteins: HREV3 with polymerase activity and HREV7, an accessory factor with unidentified activity. It has the ability to bypass pyrimidine dimers and other adducts in DNA.

  • ... Reactome ...
  • ... reactome.
  • ... It has the ability to bypass pyrimidine dimers and other adducts in DNA.
  • ... Reactome stable identifier. ... Use this URL to connect to the web page of this instance in Reactome: http://www. ...reactome.
  • ... REACTOME ...