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Searched for: REACTOME AND Extension of Telomeres [All Organisms, All Data Sources]

Your search has found 7 relevant records:

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Pathways (7)Molecules (2)
Showing Results 1 - 7 of 7 
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Pathway: Extension of Telomeres  from Reactome  [78 molecules]
Reviewed: Price, C, 2006-07-13 18:33:38.

Summary:  Reviewed: Price, C, 2006-07-13 18:33:38

  • ... Extension of Telomeres ...
  • ... Reactome ...
  • ... reactome.
  • Telomerase acts as reverse transcriptase in the elongation of telomeres (Smogorzewska and de.
  • ... Reactome stable identifier. ... Use this URL to connect to the web page of this instance in Reactome. ... REACTOME ...
  • ... Use this URL to connect to the web page of this instance ...
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Pathway: Telomere Maintenance  from Reactome  [94 molecules]
Reviewed: Price, C, 2006-07-13 18:33:38.

Summary:  Reviewed: Price, C, 2006-07-13 18:33:38

  • Maintenance of Telomeres ...
  • ... Reactome ...
  • ... reactome. ... Telomeres are protein-DNA complexes at the ends of linear chromosomes that are important for genome. ... The repeats at human telomeres. ... brbrbrDNA attrition can occur at telomeres, which can impact cell viability. ... If telomeres become critically shortened ...
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Pathway: Telomere Extension By Telomerase  from Reactome  [20 molecules]
Reviewed: Price, C, 2006-07-13 18:33:38.

Summary:  Reviewed: Price, C, 2006-07-13 18:33:38

  • Telomere Extension By Telomerase ...
  • ... Reactome ...
  • ... reactome.
  • ... Regulation of telomerase by telomeric proteins ...
  • ... Reactome stable identifier. ... Use this URL to connect to the web page of this instance in Reactome: http://www. ...reactome.
  • ... REACTOME ...
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Pathway: Translation  from Reactome  [183 molecules]
Edited: Tello-Ruiz, MK, Gillespie, ME, Gopinathrao, G, Matthews, L, 0000-00-00 00:00:00.

Summary:  Edited: Tello-Ruiz, MK, Gillespie, ME, Gopinathrao, G, Matthews, L, 0000-00-00 00:00:00

  • ... Reactome ...
  • ... reactome.
  • ... Extension of the polypeptide chain. ... Use this URL to connect to the web page of this instance in Reactome: http://www. ...reactome.
  • ... REACTOME DATABASE ID ...
  • ... Reactome stable identifier.
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Pathway: Processive synthesis on the C-strand of the telomere  from Reactome  [39 molecules]
Reviewed: Price, C, 2006-07-13 18:33:38.

Summary:  Reviewed: Price, C, 2006-07-13 18:33:38

  • ... Reactome ...
  • ... reactome. ... The process of extension is completed.
  • ... Reactome stable identifier. ... Use this URL to connect to the web page of this instance in Reactome: http://www. ...reactome.
  • ... REACTOME ...
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Pathway: Glycogen synthesis  from Reactome  [16 molecules]
Authored: 2003-02-15 00:00:00.

Summary:  Authored: 2003-02-15 00:00:00

  • ... Reactome ...
  • ... reactome.
  • ... oligomer on glycogenin, the linear extension of the glucose oligomer catalyzed by glycogen synthase.
  • ... Reactome stable identifier. ... Use this URL to connect to the web page of this instance in Reactome. ... REACTOME ...
  • ... Use this URL to connect to the web page of this instance in Reactome: http ...
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Pathway: The NLRP1 inflammasome  from Reactome  [8 molecules]
NLRP1 is activated by MDP (Faustin et al.

Summary:  NLRP1 is activated by MDP (Faustin et al. 2007). The NLRP1 inflammasome was the first to be characterized. It was described as a complex containing NALP1, ASC, caspase-1 and caspase-5 (Martinon et al. 2002). Unlike NLRP3, NLRP1 has a C-terminal extension containing a CARD domain, which has been reported to interact directly with procaspase-1, obviating a requirement for ASC (Faustin et al. 2007), though ASC was found to augment the interaction. Mouse NLRP1 has no PYD domain and would therefore not be expected to interact directly with procaspase-1. Like the NLRP3 inflammasome, K+ efflux appears to be essential for caspase-1 activation (Wickliffe et al. 2008). Ribonucleoside triphosphates (NTPs) are required for NALP1-mediated caspase-1 activation with ATP being the most efficient, Mg2+ was also required (Faustin et al. 2007). The human NLRP1 gene has 3 paralogues in mouse that are highly polymorphic. Differences between mouse strains underlie susceptibility to anthrax lethal toxin (Boyden & Dietrich 2006).

  • ... Reactome ...
  • ... reactome.
  • ... -terminal extension containing a CARD domain, which has been reported to interact directly. ... Reactome stable identifier. ... Use this URL to connect to the web page of this instance in Reactome: http://www. ...reactome.
  • ... REACTOME. ... Use this URL to connect to the web page of this instance in Reactome: http://www. ...reactome.