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Searched for: REACTOME AND Export of Viral Ribonucleoproteins from Nucleus [All Organisms, All Data Sources]

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Pathways (31)Molecules (6)
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Pathway: Export of Viral Ribonucleoproteins from Nucleus  from Reactome  [55 molecules]
Authored: Bortz, E, Garcia-Sastre, A, 2007-02-12 19:39:05.

Summary:  Authored: Bortz, E, Garcia-Sastre, A, 2007-02-12 19:39:05

  • ... Export of Viral Ribonucleoproteins from Nucleus ...
  • ... Reactome ...
  • ... reactome.
  • ... out of the nucleus, utilization of the cellular nuclear export machinery is achieved by viral adaptor proteins. ... Matrix protein (M1) is critical for export of the complex from the nucleus, mediating ...
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Pathway: NEP/NS2 Interacts with the Cellular Export Machinery  from Reactome  [53 molecules]
Authored: Bortz, E, Garcia-Sastre, A, 2007-02-12 19:39:05.

Summary:  Authored: Bortz, E, Garcia-Sastre, A, 2007-02-12 19:39:05

  • ... ribonucleoproteins: the viral matrix protein (M1) promotes export and inhibits import ...
  • ... Reactome. ... Export Machinery ...
  • The viral RNP complex is exported from the nucleus via the host cell CRM1 export pathway (Fukuda, 1997; Neumann. ... export of viral ribonucleoproteins ...
  • NEP/NS2 Interacts with the Cellular Export Machinery ...
  • ... Reactome ...
  • ... reactome.
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Pathway: Rev-mediated nuclear export of HIV-1 RNA  from Reactome  [59 molecules]
Reviewed: Kumar, A, 2007-01-31 22:47:49.

Summary:  Reviewed: Kumar, A, 2007-01-31 22:47:49

  • ... viral mRNA must be exported from the nucleus. ...Rev-mediated nuclear export of HIV-1 RNA ...
  • ... Reactome ...
  • ... reactome.
  • ... mRNA which encode the regulatory proteins Tat, Nef and Rev are exported from the nucleus while. ... export of viral RNAs to the cytoplasm (Sanchez-Velar et al.
  • ... cellular protein export pathway for the nucleocytoplasmic transport of viral RNAs ...
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Pathway: Viral RNP Complexes in the Host Cell Nucleus  from Reactome  [13 molecules]
Viral RNP is assembled in the host cell nucleus through the interaction of full-length negative strand viral RNA (vRNA) and the viral nucleocapsid (NP) and matrix (M1) proteins.

Summary:  Viral RNP is assembled in the host cell nucleus through the interaction of full-length negative strand viral RNA (vRNA) and the viral nucleocapsid (NP) and matrix (M1) proteins. Studies of interactions of the purified components in vitro and of tissue culture model systems expressing various combinations of the components have established roles for both NP and M1 proteins in the assembly of a complex that has the physical properties of vRNP purified from virions and that can be exported from the host cell nucleus (Whittaker, 1996; Huang, 2001; Baudin, 2001). Viral RNP complexes have been found in the nucleoplasm, and also in the nuclear periphery, associated with the nuclear matrix or chromatin, particularly for vRNA-containing complexes and M1 protein (Elton, 2005; Garcia-Robles, 2005; Takizawa et al., 2006).

  • ... Viral RNP Complexes in the Host Cell Nucleus ...
  • ... Reactome ...
  • ... reactome.
  • ... Viral RNP is assembled in the host cell nucleus through the interaction of full-length negative. ... from the host cell nucleus (Whittaker, 1996; Huang, 2001; Baudin, 2001). ... Viral RNP complexes have been. ... formation and nuclear export ...
  • ... Reactome stable identifier.
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Pathway: Influenza Viral RNA Transcription and Replication  from Reactome  [143 molecules]
Authored: Bortz, E, Garcia-Sastre, A, 2007-02-12 19:39:05.

Summary:  Authored: Bortz, E, Garcia-Sastre, A, 2007-02-12 19:39:05

  • Influenza Viral RNA Transcription and Replication ...
  • ... Reactome ...
  • ... reactome.
  • Influenza Viral RNA Transcription. ... nucleus, the viral negative-strand RNA (vRNA) serves as a template for the synthesis both of capped. ... enter the nucleus as part of the viral RNP complex. ... After the first round of viral mRNA synthesis.
  • Trafficking of viral genomic RNA into and out of the nucleus: influenza ...
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Pathway: snRNP Assembly  from Reactome  [76 molecules]
Small nuclear ribonucleoproteins (snRNPs) are crucial for pre-mRNA processing to mRNAs.

Summary:  Small nuclear ribonucleoproteins (snRNPs) are crucial for pre-mRNA processing to mRNAs. Each snRNP contains a small nuclear RNA (snRNA) and an extremely stable core of seven Sm proteins. The U6 snRNA differs from the other snRNAs; it binds seven Sm-like proteins and its assembly does not involve a cytoplasmic phase. The snRNP biogenesis pathway for all of the other snRNAs is complex, involving nuclear export of snRNA, Sm-core assembly in the cytoplasm and re-import of the mature snRNP. The assembly of the snRNA:Sm-core is carried out by the survival of motor neurons (SMN) complex. The SMN complex stringently scrutinizes RNAs for specific features that define them as snRNAs and binds the RNA-binding Sm proteins.

  • ... Reactome ...
  • ... reactome.
  • Small nuclear ribonucleoproteins (snRNPs) are crucial. ... stable core of seven Sm proteins. ... The U6 snRNA differs from the other snRNAs; it binds seven Sm-like. ... of the other snRNAs is complex, involving nuclear export of snRNA, Sm-core assembly in the cytoplasm. ... this URL to connect to the web page of this instance in Reactome: http://www. ...reactome.
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Pathway: Transcription of the HIV genome  from Reactome  [174 molecules]
Reviewed: Peterlin, BM, 2005-01-05 00:00:00.

Summary:  Reviewed: Peterlin, BM, 2005-01-05 00:00:00

  • ... Reactome ...
  • ... reactome.
  • ... ) viral mRNAs are generated by alternative splicing. ... The activities of Tat and Rev create two phases. ... sequence, is required for efficient elongation of the HIV-1 transcript. ... In the early phase of viral. ... In the late phase, Rev regulates nuclear export of HIV-1 mRNAs, repressing expression of the early regulatory mRNAs and promoting expression of viral structural proteins ...
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Pathway: Formation and Maturation of mRNA Transcript  from Reactome  [403 molecules]
Edited: Joshi-Tope, G, 0000-00-00 00:00:00.

Summary:  Edited: Joshi-Tope, G, 0000-00-00 00:00:00

  • ... of capping, splicing and polyadenylation. ...p The export of mRNA from the nucleus and mRNA splicing are also. ... counterparts transcribed from a complementary DNA (cDNA). ... This effect of splicing on export is due. ...Formation and Maturation of mRNA Transcript ...
  • ... Reactome ...
  • ... reactome. ... to be transported out of the nucleus, it has to undergo three major processing events to produce a fully translatable mRNA. ... These comprise capping, splicing out of introns from within the body of the pre-mRNA ...
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Pathway: CDK-mediated phosphorylation and removal of Cdc6  from Reactome  [73 molecules]
As cells enter S phase, HsCdc6p is phosphorylated by CDK promoting its export from the nucleus (see Bell and Dutta 2002).

Summary:  As cells enter S phase, HsCdc6p is phosphorylated by CDK promoting its export from the nucleus (see Bell and Dutta 2002).

  • ... of Cdc6 ...
  • As cells enter S phase, HsCdc6p is phosphorylated by CDK promoting its export from the nucleus (see Bell and Dutta 2002).
  • ... Reactome ...
  • ... reactome.
  • ... Reactome stable identifier. ... Use this URL to connect to the web page of this instance in Reactome. ... REACTOME ...
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Pathway: Late Phase of HIV Life Cycle  from Reactome  [232 molecules]
Reviewed: Peterlin, BM, 2005-01-05 00:00:00.

Summary:  Reviewed: Peterlin, BM, 2005-01-05 00:00:00

  • ... of the HIV gene products and the assembly of viral particles. ... The assembly of viral particles will be covered in a later release of Reactome. ... HIV-1 gene expression is regulated by both cellular and viral. ...Late Phase of HIV Life Cycle ...
  • ... Reactome ...
  • ... reactome.
  • ... Rev functions by promoting the nuclear export of unspliced and partially spliced transcripts. ... this URL to connect to the web page of this instance in Reactome: http://www. ...reactome.