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Searched for: REACTOME AND Double-Strand Break Repair [All Organisms, All Data Sources]

Your search has found 18 relevant records:

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Pathways (18)Molecules (32)
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Pathway: Processing of DNA double-strand break ends  from Reactome  [8 molecules]
The processing of DNA double strand breaks requires resectioning of the broken ends followed by the association of RPA complexes with ssDNA.

Summary:  The processing of DNA double strand breaks requires resectioning of the broken ends followed by the association of RPA complexes with ssDNA.

  • Processing of DNA double-strand break ends ...
  • ... Reactome ...
  • ... reactome.
  • The processing of DNA double strand breaks requires resectioning of the broken ends followed. ... Surveillance and Repair (Keith Caldecott, editor)1-40 ...
  • Origin, Recognition, Signaling and Repair of DNA Double-Strand Breaks in Mammalian Cells ...
  • ... Reactome stable identifier ...
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Pathway: Homologous Recombination Repair  from Reactome  [65 molecules]
Edited: Matthews, L, 0000-00-00 00:00:00.

Summary:  Edited: Matthews, L, 0000-00-00 00:00:00

  • ... processing of the ends of the DNA double-strand break, homologous DNA pairing and strand exchange, repair DNA. ... information encoded by homologous sequence to repair double-strand breaks (DSBs).
  • DNA double-strand breaks: signaling, repair.
  • Origin, Recognition, Signaling and Repair of DNA Double-Strand. ...Homologous Recombination Repair ...
  • ... Reactome ...
  • ... reactome.
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Pathway: ATM mediated response to DNA double-strand break  from Reactome  [10 molecules]
Authored: Matthews, L, 2003-11-18 00:00:00.

Summary:  Authored: Matthews, L, 2003-11-18 00:00:00

  • ATM mediated response to DNA double-strand break ...
  • ... Reactome ...
  • ... reactome.
  • Detection of DNA double-strand breaks. ... leads to the recruitment of repair proteins and subsequent repair of the damaged DNA. ... ATM is one of the primary candidate sensors in double-strand break repair.
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Pathway: Double-Strand Break Repair  from Reactome  [81 molecules]
Edited: Matthews, L, 0000-00-00 00:00:00.

Summary:  Edited: Matthews, L, 0000-00-00 00:00:00

  • ... Double-Strand Break Repair ...
  • ... Reactome ...
  • ... reactome.
  • Pathways of DNA double-strand break repair during the mammalian cell cycle.
  • ... Reactome stable identifier. ... Double-strand breaks (DSBs), one of the most dangerous type of DNA damage along ...
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Pathway: Presynaptic phase of homologous DNA pairing and strand exchange  from Reactome  [18 molecules]
The presynaptic phase of homologous DNA pairing and strand exchange begins with the displacement of RPA from ssDNA, followed by the association of RAD51 with BRCA2, formation of RAD52 heptameric ring structure complexes on ssDNA, association of RAD52 with the RPA complex, association of RAD52 with ssDNA at resected ends of double-strand break and assembly of the RAD51-ssDNA nucleoprotein complex.

Summary:  The presynaptic phase of homologous DNA pairing and strand exchange begins with the displacement of RPA from ssDNA, followed by the association of RAD51 with BRCA2, formation of RAD52 heptameric ring structure complexes on ssDNA, association of RAD52 with the RPA complex, association of RAD52 with ssDNA at resected ends of double-strand break and assembly of the RAD51-ssDNA nucleoprotein complex.

  • ... with the RPA complex, association of RAD52 with ssDNA at resected ends of double-strand break and assembly. ..., Recognition, Signaling and Repair of DNA Double-Strand Breaks in Mammalian Cells ...
  • ... Reactome ...
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Pathway: Homologous recombination repair of replication-independent double-strand breaks  from Reactome  [65 molecules]
Homologous recombination repair of replication-independent double-strand breaks requires the activation of ATM followed by ATM mediated phosphorylation of DNA repair proteins.

Summary:  Homologous recombination repair of replication-independent double-strand breaks requires the activation of ATM followed by ATM mediated phosphorylation of DNA repair proteins. DNA repair and signaling proteins are then recruited to double-strand breaks. The ends of the DNA double strand breaks must be resectioned and RPA complexes associate with the resulting ssDNA. Homologous DNA pairing and strand exchange then occurs followed by DNA repair synthesis and resolution of D-loop structures.

  • Homologous recombination repair of replication-independent double-strand breaks ...
  • ... Reactome. ... recombination repair of replication-independent double-strand breaks ...
  • Homologous recombination repair of replication-independent double-strand breaks requires the activation of ATM followed by ATM mediated phosphorylation of DNA repair proteins. ... DNA repair and signaling proteins are then recruited to double-strand breaks. ... The ends of the DNA double strand breaks must be resectioned and RPA ...
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Pathway: Homologous recombination repair of replication-dependent double-strand breaks
Authored: Matthews, L, 2003-11-18 00:00:00.

Summary:  Authored: Matthews, L, 2003-11-18 00:00:00

  • Homologous recombination repair of replication-dependent double-strand breaks ...
  • ... Reactome. ... recombination repair of replication-dependent double-strand breaks ...
  • Homologous recombination repair of replication-dependent DNA double-strand breaks will be described in a later version of GKB.
  • ... Reactome stable identifier. ... Use this URL to connect to the web page of this instance in Reactome: http://www. ...reactome.
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Pathway: MRN complex relocalizes to nuclear foci  from Reactome  [10 molecules]
Authored: Matthews, L, 2003-11-23 12:20:00.

Summary:  Authored: Matthews, L, 2003-11-23 12:20:00

  • ... to double-strand breaks and have been implicated in DNA end-processing during homologous recombination repair (Trujillo et al. ... The MRN complex may function as a bridge between double-strand break.
  • In situ visualization of DNA double-strand break repair in human fibroblasts.
  • ... Reactome ...
  • ... reactome.
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Pathway: Recruitment of repair and signaling proteins to double-strand breaks  from Reactome  [19 molecules]
Authored: Matthews, L, 2003-11-18 00:00:00.

Summary:  Authored: Matthews, L, 2003-11-18 00:00:00

  • Recruitment of repair and signaling proteins to double-strand breaks ...
  • ... Reactome ...
  • ... reactome.
  • ... relocalize to nuclear foci that are believed to correspond to the sites of double-strand breaks. ... (B,C) Induction of a DNA double-stranded break (DSB), modification of chromatin ...
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Pathway: Nonhomologous End-joining (NHEJ)  from Reactome  [19 molecules]
Authored: Lees-Miller, S, 2003-07-14 15:03:25.

Summary:  Authored: Lees-Miller, S, 2003-07-14 15:03:25

  • ... of double-strand break repair.
  • ... Reactome stable identifier. ... of a DNA double-strand break (DSB) induced by a DNA-damaging agent such as ionizing radiation. ... Nonhomologous end joining: repair of DNA double strand breaks after ionizing radiation ...
  • ... -dependent protein kinase catalytic subunit in DNA strand break rejoining.
  • Sensing and repairing DNA double-strand breaks ...