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Searched for: REACTOME AND Activated TLR4 signalling [All Organisms, All Data Sources]

Your search has found 189 relevant records:

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Pathways (189)Molecules (242)
Showing Results 1 - 10 of 189  | Next 10
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Pathway: Activated TLR4 signalling  from Reactome  [170 molecules]
Reviewed: Gillespie, ME, 2010-11-30.

Summary:  Reviewed: Gillespie, ME, 2010-11-30

  • ... Activated TLR4 signalling ...
  • ... Reactome ...
  • ... reactome.
  • ... TLR4 is unique among the TLR family in its. ... is activated by the pair of the adapters Mal or TIRAP (Toll/interleukin-1-receptor (TIR)-domain-containing. ... The second pathway is activated by the adapters TRIF (TIR-domain-containing adapter protein ...
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Pathway: MyD88:Mal cascade initiated on plasma membrane  from Reactome  [140 molecules]
Edited: de Bono, B, 2005-08-16 10:54:15.

Summary:  Edited: de Bono, B, 2005-08-16 10:54:15

  • ... Reactome ...
  • ... reactome. ... The first known downstream component of TLR4 and TLR2 signaling is the adaptor MyD88. ... been described for TLR4 and TLR2 signaling. ... with the activated TLRs, whereas the DD modules recruit serine/threonine kinases. ... of the activator protein-1 (AP-1) transcription factor family, Jun and Fos, are activated, and both AP-1 ...
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Pathway: MyD88-independent cascade initiated on plasma membrane  from Reactome  [125 molecules]
Edited: de Bono, B, 2005-08-16 10:54:15.

Summary:  Edited: de Bono, B, 2005-08-16 10:54:15

  • ... TRAM is thought to bridge between activated TLR4 and TRIF. ... Although recent studies suggest that TLR4 activates TRIF-signaling in endosome/lysosome after relocation from the cell surface, the data shown here represent the current model where TLR4 signaling cascade.
  • MD-2: the Toll 'gatekeeper' in endotoxin signalling ...
  • ... Reactome.
  • ... Reactome ...
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Pathway: NFkB and MAP kinases activation mediated by TLR4 signaling repertoire  from Reactome  [116 molecules]
Edited: Shamovsky, V, 2010-11-15.

Summary:  Edited: Shamovsky, V, 2010-11-15

  • NFkB and MAP kinases activation mediated by TLR4 signaling repertoire ...
  • ... Reactome ...
  • ... activation mediated by TLR4 signaling repertoire ...
  • Mitogen activated protein kinase (MAPK) cascade, one of the most ancient and evolutionarily conserved. .../ulpERK1 and ERK2 are activated in response to growth stimuli. ... Both JNKs and p38-MAPK are activated in response to a variety of cellular and environmental stresses. ... The MAP kinases are activated by dual ...
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Pathway: Retrograde neurotrophin signalling  from Reactome  [23 molecules]
Authored: Nasi, S, Annibali, D, 2006-10-10 09:07:07.

Summary:  Authored: Nasi, S, Annibali, D, 2006-10-10 09:07:07

  • Retrograde neurotrophin signalling ...
  • ... Reactome ...
  • ... reactome.
  • ... to its activated TRK receptor, together with activated downstream signalling proteins, transported. ... Neurotrophin-TRK complexes can be internalized and enter signalling vesicles, which travel retrogradely over long distances from distal nerve terminals to neuronal cell bodies. ... Such retrograde signalling ...
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Pathway: G alpha (q) signalling events  from Reactome  [53 molecules]
Edited: Jupe, S, 2009-03-09 15:04:20.

Summary:  Edited: Jupe, S, 2009-03-09 15:04:20

  • G alpha (q) signalling events ...
  • ... Reactome ...
  • ... reactome.
  • The classic signalling route for G alpha (q) is activation of phospholipase C. ... Gq participates in many other signalling events including direct. ... Use this URL to connect to the web page of this instance in Reactome: http://www. ...reactome.
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Pathway: PKA activation in glucagon signalling  from Reactome  [14 molecules]
Authored: Gopinathrao, G, D'Eustachio, P, 2005-05-19 14:01:31.

Summary:  Authored: Gopinathrao, G, D'Eustachio, P, 2005-05-19 14:01:31

  • PKA activation in glucagon signalling ...
  • ... Reactome ...
  • ... reactome.
  • ... , but the specific isoform activated in response to glucagon signaling has not yet been identified.
  • ... Reactome stable identifier. ... Use this URL to connect to the web page of this instance in Reactome: http://www. ...reactome.
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Pathway: SHC-related events  from Reactome  [50 molecules]
SHC is one of the mediators of insulin signalling events.

Summary:  SHC is one of the mediators of insulin signalling events. It is activated by phosphorylation and triggers a cascade of events involving SOS, RAF and the MAP kinases.

  • ... signalling events. ... It is activated by phosphorylation and triggers a cascade of events involving SOS, RAF.
  • ... Reactome ...
  • ... reactome.
  • ... this URL to connect to the web page of this instance in Reactome: http://www. ...reactome.
  • ... REACTOME DATABASE ID ...
  • ... Reactome stable identifier. ... Use this URL to connect to the web page of this instance in Reactome: http ...
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Pathway: Signaling by BMP  from Reactome  [33 molecules]
Reviewed: Heldin, CH, 2007-11-12 14:50:01.

Summary:  Reviewed: Heldin, CH, 2007-11-12 14:50:01

  • ... Reactome ...
  • ... reactome.
  • ... The TGF-beta/BMP (bone morphogenetic protein) pathway incorporates several signalling pathways that share most, but not all, components of a central signal transduction engine. ... The general signalling scheme is rather simple: upon binding of a ligand, an activated plasma membrane receptor complex is formed, which passes on the signal towards the nucleus through a phosphorylated receptor-activated ...
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Pathway: Signalling to p38 via RIT and RIN  from Reactome  [50 molecules]
Authored: Nasi, S, Annibali, D, 2006-10-10 09:07:07.

Summary:  Authored: Nasi, S, Annibali, D, 2006-10-10 09:07:07

  • ... Signalling to p38 via RIT and RIN ...
  • ... Reactome ...
  • ... reactome.
  • ... similar signalling properties and are activated by NGF through unknown exchange factors.
  • ... Reactome stable identifier. ... Use this URL to connect to the web page of this instance in Reactome: http://www. ...reactome.