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Protein: MYL9_MOUSE

Myosin regulatory light polypeptide 9

FUNCTION: Myosin regulatory subunit that plays an important role in regulation of both smooth muscle and nonmuscle cell contractile activity via its phosphorylation. Implicated in cytokinesis, receptor capping, and cell locomotion (By similarity). more...

SUBUNIT: Myosin is an hexamer of 2 heavy chains and 4 light chains (By similarity).

PTM: Phosphorylation increases the actin-activated myosin ATPase activity and thereby regulates the contractile activity. It is required to generate the driving force in the migration of the cells but not necessary for localization of myosin-2 at the leading edge (By similarity). MISCELLANEOUS: This chain binds calcium (By similarity).

SIMILARITY: Contains 3 EF-hand domains.

GENE SYNONYMS: Myrl2.

COPYRIGHT: Protein annotation is derived from the UniProt Consortium (http://www.uniprot.org/). Distributed under the Creative Commons Attribution-NoDerivs License.

No pathway or interaction information available for this record.

 

Organism:

  • Mus musculus

Gene Symbol:

  • Myl9

Synonyms:

  • Myosin regulatory light chain 9
  • Myosin regulatory light chain 2, smooth muscle isoform

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