Transposon Ty3-I Gag polyprotein
FUNCTION: Nucleocapsid protein p9 (NC) forms the nucleocore that coats the retro-elements dimeric RNA. Binds these RNAs through its zinc fingers (By similarity). Promotes primer tRNA(i)-Met annealing to the multipartite primer-binding site (PBS), dimerization of Ty3 RNA and initiation of reverse transcription.
SUBCELLULAR LOCATION: Cytoplasm.
ALTERNATIVE PRODUCTS: Event=Ribosomal frameshifting; Named isoforms=2; Comment=The Gag-Pol polyprotein is generated by a +1 ribosomal frameshift; Name=Transposon Ty3-I Gag polyprotein; IsoId=Q99219-1; Sequence=Displayed; Note=Produced by conventional translation; Name=Transposon Ty3-I Gag-Pol polyprotein; IsoId=Q7LHG5-1; Sequence=External; Note=Produced by +1 ribosomal frameshifting between codon Ala-285 and Val-286 of the YIL082W ORF;
DOMAIN: The N-terminal domain of NC, but not its zinc finger, is required for nucleoprotein complex formation and its chaperone activities. MISCELLANEOUS: Retrotransposons are mobile genetic entities that are able to replicate via an RNA intermediate and a reverse transcription step. In contrast to retroviruses, retrotransposons are non-infectious, lack an envelope and remain intracellular. Ty3 retrotransposons belong to the gypsy-like elements (metaviridae).
SIMILARITY: Contains 1 CCHC-type zinc finger.
SEQUENCE CAUTION: Sequence=AAA35183.1; Type=Erroneous initiation;
GENE SYNONYMS: YILWTy3-1 GAG.
COPYRIGHT: Protein annotation is derived from the UniProt Consortium (http://www.uniprot.org/). Distributed under the Creative Commons Attribution-NoDerivs License.