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Protein: GGT6_HUMAN

Gamma-glutamyltransferase 6

FUNCTION: Cleaves glutathione conjugates (By similarity). CATALYTIC ACTIVITY: (5-L-glutamyl)-peptide + an amino acid = peptide + 5-L-glutamyl amino acid. CATALYTIC ACTIVITY: Glutathione + H(2)O = L-cysteinylglycine + L- glutamate. more...

PATHWAY: Sulfur metabolism; glutathione metabolism.

SUBUNIT: Heterodimer composed of the light and heavy chains. The active site is located in the light chain (By similarity).

SUBCELLULAR LOCATION: Membrane; Single-pass type II membrane protein (By similarity).

ALTERNATIVE PRODUCTS: Event=Alternative splicing; Named isoforms=2; Name=1; IsoId=Q6P531-1; Sequence=Displayed; Name=2; IsoId=Q6P531-2; Sequence=VSP_030451;

SIMILARITY: Belongs to the gamma-glutamyltransferase family.

COPYRIGHT: Protein annotation is derived from the UniProt Consortium (http://www.uniprot.org/). Distributed under the Creative Commons Attribution-NoDerivs License.

 

Organism:

  • Homo sapiens

Gene Symbol:

  • GGT6

Synonyms:

  • 2.3.2.2
  • Gamma-glutamyltransferase 6 light chain
  • GGT 6
  • Gamma-glutamyltranspeptidase 6
  • Gamma-glutamyltransferase 6 heavy chain

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