Protein: GGT6_HUMAN
Gamma-glutamyltransferase 6
PATHWAY: Sulfur metabolism; glutathione metabolism.
SUBUNIT: Heterodimer composed of the light and heavy chains. The active site is located in the light chain (By similarity).
SUBCELLULAR LOCATION: Membrane; Single-pass type II membrane protein (By similarity).
ALTERNATIVE PRODUCTS: Event=Alternative splicing; Named isoforms=2; Name=1; IsoId=Q6P531-1; Sequence=Displayed; Name=2; IsoId=Q6P531-2; Sequence=VSP_030451;
SIMILARITY: Belongs to the gamma-glutamyltransferase family.
COPYRIGHT: Protein annotation is derived from the UniProt Consortium (http://www.uniprot.org/). Distributed under the Creative Commons Attribution-NoDerivs License.
Organism:
- Homo sapiens
Gene Symbol:
- GGT6
Synonyms:
- 2.3.2.2
- Gamma-glutamyltransferase 6 light chain
- GGT 6
- Gamma-glutamyltranspeptidase 6
- Gamma-glutamyltransferase 6 heavy chain
Links:
Stable Link:
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FUNCTION: Cleaves glutathione conjugates (By similarity). CATALYTIC ACTIVITY: (5-L-glutamyl)-peptide + an amino acid = peptide + 5-L-glutamyl amino acid. CATALYTIC ACTIVITY: Glutathione + H(2)O = L-cysteinylglycine + L- glutamate. more...