Homeobox protein SIX3
SUBCELLULAR LOCATION: Nucleus.
ALTERNATIVE PRODUCTS: Event=Alternative splicing; Named isoforms=2; Name=SIX3B; IsoId=Q62233-1; Sequence=Displayed; Name=SIX3A; IsoId=Q62233-2; Sequence=VSP_002291, VSP_002292; DEVELOPMENTAL STAGE: First expressed at E6.5 of embryo development around the anterior border. At E8.5, expression is found over the anterior neural plate. At E9.5, in the diencephalic part of the ventral forebrain, optic vesicles, olfactory placodes and Rathke pouch. In later stages, present in hypothalamus, eyes and pituitary.
SIMILARITY: Belongs to the SIX/Sine oculis homeobox family.
SIMILARITY: Contains 1 homeobox DNA-binding domain.
SEQUENCE CAUTION: Sequence=CAA62379.1; Type=Erroneous initiation;
COPYRIGHT: Protein annotation is derived from the UniProt Consortium (http://www.uniprot.org/). Distributed under the Creative Commons Attribution-NoDerivs License.