Send us your feedback.  Sign up for Pathway Commons announcements.  RSS Logo RSS Feed

Protein: LEP_MOUSE

Leptin

FUNCTION: May function as part of a signaling pathway that acts to regulate the size of the body fat depot. An increase in the level of LEP may act directly or indirectly on the CNS to inhibit food intake and/or regulate energy expenditure as part of a homeostatic mechanism to maintain constancy of the adipose mass. more...

SUBCELLULAR LOCATION: Secreted (Probable).

DISEASE: Note=Defects in Lep are the cause of profound obesity and type II diabetes.

SIMILARITY: Belongs to the leptin family.

GENE SYNONYMS: Ob.

COPYRIGHT: Protein annotation is derived from the UniProt Consortium (http://www.uniprot.org/). Distributed under the Creative Commons Attribution-NoDerivs License.

No pathway or interaction information available for this record.

 

Organism:

  • Mus musculus

Gene Symbol:

  • Lep

Synonyms:

  • Obesity factor

Neighborhood Map:

  Loading...

Stable Link:

  • Link to this page
    Link to this page
    Paste link in email or IM:
    Paste HTML to embed in website:
Filter by Data Source:
  • All Data Sources
Filter by Organism:
  • All Organisms

[Update Filter Settings]