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Search Pathway Commons:

To get started, enter a gene name, gene identifier or pathway name in the text box above. For example: BRCA1, P38398 or mTOR.

To restrict your search to specific data sources or specific organisms, update your global filter settings.

What's New:

  • New!  July 2, 2009:
    • Batch Download of all Pathway Commons data in multiple file formats is now available.
    • Systems Biology Center New York - IMID data set (December 17, 2008 Version 27).
    • Latest Reactome data set (June 24, 2009 Version 29).
    • Latest HumanCyc data set (June 22, 2009 Version 13.1).
    • All yeast proteins are now annotated with UniProt functional annotation.
  • March 1, 2009:
    • BioGRID data set (January 28, 2009 Version 2.0.49).
    • Latest Reactome data set (December 17, 2008 Version 27).
    • Latest HumanCyc data set (October 15, 2008 Version 12.5).
    • Neighborhood maps added to protein pages.
  • July 24, 2008:
    • Latest Reactome data set (June 30, 2008 Version 25).
    • All human, mouse and rat proteins are now annotated with UniProt functional annotation.
    • Improved search support for gene symbols.
    • Stable links now available for linking out to protein pages.
  • April 1, 2008: New features for visualizing pathways using Cytoscape [Details].
  • February 1, 2008: New data sources, including: HPRD, IntAct, and MINT. Improved web service API.
  

Using Pathway Commons:

Biologists: Browse and search pathways across multiple valuable public pathway databases.

Computational biologists: Download an integrated set of pathways in BioPAX format for global analysis.

Software developers: Build software on top of Pathway Commons using our web service API. Download and install the cPath software to create a local mirror.

Current Data Sources:

Pathway Commons currently contains the following data sources (batch download):

Pathway Commons Quick Stats:
Number of Pathways: 1,449
Number of Interactions: 421,395
Number of Physical Entities: 88,509
Number of Organisms: 441

Integration of additional data sources is planned in the near future. For a comprehensive directory of interaction and pathway databases, please refer to Pathguide.