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Using Pathway Commons:

Biologists: Browse and search pathways across multiple valuable public pathway databases.

Computational biologists: Download an integrated set of pathways in BioPAX format for global analysis.

Software developers: Build software on top of Pathway Commons using our web service API. Download and install the cPath software to create a local mirror.

What's New:

  • New!  July 24, 2008:
    • Latest Reactome data set (June 30, 2008 Version 25).
    • All human, mouse and rat proteins are now annotated with UniProt functional annotation.
    • Improved search support for gene symbols.
    • ExecuteGetParentsXmlResponse
    • Stable links now available for linking out to protein pages.
    • Numerous bug fixes and performance improvements.
  • April 1, 2008: New features for visualizing pathways using Cytoscape [Details].
  • February 1, 2008: New data sources, including: HPRD, IntAct, and MINT. Improved web service API.
 

Current Data Sources:

Pathway Commons currently contains the following data sources:

Cancer Cell Map, Release: 1.0 [19-May-06]
Browse
HPRD [01-Sep-07]
Browse
HumanCyc, Release: 10.5 [18-Sep-06]
Browse
IntAct [14-Dec-07]
Browse
MINT [21-Dec-07]
Browse
NCI / Nature Pathway Interaction Database [28-Jan-08]
Browse
Reactome, Release: 25 [30-Jun-08]
Browse
Pathway Commons Quick Stats:
Number of Pathways: 1,157
Number of Interactions: 258,636
Number of Physical Entities: 80,827
Number of Organisms: 1,005

Integration of additional data sources is planned in the near future. For a comprehensive directory of interaction and pathway databases, please refer to Pathguide.